Analytical Instruments

Nucleic Acid Purification is also known as nucleic acid extraction or nucleic acid isolation is a fundamental technique in molecular biology and genetics that allows isolation, purification and concentration of nucleic acids, DNA, and RNA molecules from biological samples. The sample is first subjected to mechanical disruption or enzymatic digestion that leads to the cell lysis and releases the nucleic acid molecules that are precipitated followed by purification to remove impurities such as lipids, proteins and cellular debris. Further, the nucleic acids are concentrated and eluted to obtain high-purity nucleic acid samples. It has various practical applications in clinical virus diagnosis, microbial detection, gene sequencing, southern blot method and polymerase chain reaction, etc.